DCLK1 immunoreactivity in colorectal neoplasia
نویسندگان
چکیده
منابع مشابه
DCLK1 immunoreactivity in colorectal neoplasia
INTRODUCTION Microtubule-associated doublecortin and CaM kinase-like-1 (DCLK1) is a novel candidate marker for intestinal stem cells. The aim of our study was to assess DCLK1 immunoreactivity in colorectal carcinogenesis and its correlation with prognosis. METHODS DCLK1 immunostaining was performed in colorectal tissue from 71 patients, including 18 adenomatous polyps, 40 primary adenocarcino...
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Doublecortin-like kinase (Dclk1), a gene involved in neurogenesis, has recently been found expressed in single cells of the human and murine adult gastrointestinal tract. Currently, there are opposing opinions on the exact identity and functional characteristics of DCLK1 positive cells. Some view them as gastrointestinal stem cells that fuel the self-renewal process, whereas others view them as...
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ژورنال
عنوان ژورنال: Clinical and Experimental Gastroenterology
سال: 2012
ISSN: 1178-7023
DOI: 10.2147/ceg.s30281